New Discoveries

Overview

Few people pay attention to how the chemicals and molecular ingredients of our everyday life are made. Traditionally, most come from petrochemical processing or extraction from natural sources such as plants or animals. However, both methods face major challenges. Petrochemicals are ultimately unsustainable and contribute to increasing levels of atmospheric carbon dioxide. Natural products derived from native sources require inefficient use of land and impose a heavy burden on other natural resources, as most exist in low concentrations and are difficult to extract and purify.

To overcome these challenges, Conagen’s scientists and engineers use modern synthetic biology tools to develop novel and renewable bio-based production platforms. We have designed chassis organisms for the production of various molecular classes. We are constantly pushing the frontiers of bio-manufacturing and discovering innovative solutions to improve our everyday lives.

 Conagen Platform

 

Terpenoids

Terpenoids are one of the most diverse secondary metabolite classes found in nature. Conagen has developed one of the most high-yielding fermentation platforms for producing sesquiterpenes, diterpenes, triterpenes, carotenoids, and related derivatives thereof.

Aromatic amino acids-derived compounds

Phenylalanine, tyrosine, and tryptophan are three of the most important aromatic amino acids. They are used extensively in the feed and food industries. Many important pharmaceutical compounds, flavors, and industrial polymers are derived from these aromatic amino acids.
Conagen’s bacterial production platforms have been sculpted to make
this group of compounds.

Sugars and cell wall polymers

Carbohydrate synthesis and conversion is at the center of cellular metabolism. Conagen’s scientists and engineers have developed an array of carbohydrate production technologies; from next generation natural sweeteners to essential pharmaceutical ingredients.

Proteins and peptides

Nanotechnologies and computational biology play a big role in Conagen’s protein and peptide research, development and production. We are using our unique production systems to bring down the cost of difficult-to-produce proteins, and developing a variety of protein-based products for consumers and industry.

Secondary metabolic compounds

Secondary metabolites are the most important source of new natural products. Reconstruction of these metabolic pathways in our robust chassis organisms enables us to make a range of important bio-products including natural pigments, functional ingredients, nutritional supplements, flavors, and fragrances.