Few people pay attention to how we obtain the chemicals and molecular ingredients of our everyday life. Traditionally, they are from petrochemical processing or extraction from natural sources such as plants or animals. However, both methods face major challenges. Petrochemical processing depends on limited petroleum supply and may cause environmental pollutions. Natural product extraction can place a heavy burden on natural resources, and many low concentration ingredients are difficult to obtain.
To overcome these challenges, Conagen’s scientists and engineers focus on using modern synthetic biology tools to develop novel and renewable bio-based production platforms. We have engineered specifically-designed chassis organisms for the production of various molecules. We are constantly pushing the frontiers of bio-manufacturing and discovering innovative solutions.
Terpenoids are one of the most diverse secondary compounds found in nature. Conagen has developed one of the most high-yielding fermentation platforms for producing sesquiterpenes, diterpenes, triterpenes, carotenoids, and their degradation as well as modification products.
Aromatic amino acids-derived compounds
Phenylalanine, tyrosine, and tryptophan are three of the most important aromatic amino acids. They are used extensively in feed and food industries. Many of the important pharmaceutical compounds, flavors, and industrial polymers are derived from these aromatic amino acids as well. Conagen’s bacteria-based production platforms are primed to make this group of compounds.
Sugars and cell wall polymers
Carbohydrate synthesis and conversion is at the center of cellular metabolism. Conagen’s scientists and engineers have developed a myriad of carbohydrate technologies to produce such varied molecules, from next generation natural sweeteners to essential pharmaceutical ingredients.
Proteins and peptides
Who would imagine nanotechnologies and computational biology played such a big role in Conagen’s protein and peptide research and production? We are using our unique production system to bring down the cost of difficult-to-produce proteins, and developing protein-based products for consumers and industries.
Secondary metabolic compounds
Secondary metabolites are the biggest group of natural products. By re-construction of these pathways in our production chassis, we are making a range of bio-products including natural pigments, functional ingredients, nutritional supplements, flavors, and fragrances.